Chennai
gets a niche
Center for Medical Genetics
(Non
Profit Organization – Dedicated to the Society)
Offering end to end Genetic
Diagnostic Solutions
with a an affordable cost and Quick Turnaround
Time
Center for Medical
Genetics (CMG) (a unit of GenVams TRUST) is a non-profit, service - oriented
professional genetic testing laboratory in Chennai. Our founding principle and
primary goal is “PREVENTION OF BIRTH DEFECTS”. Under this project we are in the
process of establishing a comprehensive Medical Genetics Service. To begin
with, we have established a cytogenetic laboratory and genetic counseling
service. Chromosomal disorders are the major cause of birth defects, which
afflict one out of every 160 children born. Cytogenetic testing for chromosome
anomalies and counselling could help and save the family and the community from
undue emotional and financial burden.
This
Center for Medical Genetics is functioning under the guidance
of
Dr.
Vaithilingam G Dev, PhD -
has nearly 40 years of experience in chromosomal and genetic disorders (both
diagnostic and research) in the USA.
Dr.
G Kumaramanickavel, MD -
has around 25 years of experience in the field of medical genetics, molecular
diagnostics and research and genetic counseling in India.
Center for Medical Genetics
Offering Services are
Chromosome analysis of the following specimen types and turn around time
- Peripheral blood lymphocytes (7 days) (Currently offered)
- Amniotic fluid (7 – 10 days) (To be offered)
- Chorionic villus sampling (6-8 days) (To be offered)
- Fetal blood specimen (3-4 days) (To be offered)
- Products of conception (10-14 days) (To be offered)
- Lymphoproliferative Disorders
- Bone marrow specimens (3- 6 days) (Currently offered)
The
karyotypes and reports will be reviewed and approved by a Clincal
Cytogeneticist, certified by the American Board of Medical Genetics. When
applicable, the report will include information relevant for genetic
counseling.
FLUORESCENCE IN SITU HYBRIDIZATION (FISH) (Currently offered)
- Peripheral blood lymphocytes (7-10 Days)
- Amniotic fluid (24 hours to 6 days) (To be offered)
- Chorionic villus sampling (6-8 days) (To be offered)
- Chorionic villus sampling (24 hours – 5 days) (To be offered)
- Fetal blood specimen (24 hours) (To be offered)
- Bone marrow specimens (7-10 Days)
FISH studies
will be performed in conjunction with conventional cytogenetics.
Chip-based array technology
Provides
information at a higher resolution aiding in the detection of submicroscopic
chromosomal abnormalities.
Common indications for chromosomal studies
Pregnancy
- Maternal Age
- Abnormal Tri/Quad Screen results
- Family History of Genetic abnormalities
- Recurrent miscarriage
Newborns
- Down Syndrome
- Edward Syndrome
- Patau Syndrome
- Multiple Congenital Anomalies
- Heart Malformations
- Ambiguous Genitalia
- Undescended Testis (Sex Determination)
Pediatric/Adult
- Lack of Normal Physiological Development
- Dysmorphic Features
- Autistic Spectrum Disorder
- Mental Disability of Unknown Cause
- Primary/Secondary Amenorrhea
- Gynecomastia and Oligospermia
- Infertility (Male and Female)
Cancer
- Anemia
- Leukemia
- Lymphoma
- Myelodysplastic Syndrome
- Myeloproliferative Disorders
- Lymphoproliferative Disorders
- Bone Marrow Engraftment
- Solid Tumors
Chromosomal studies
- Peripheral blood karyotyping
- Bone Marrow karyotyping
Genetic counseling
- Interpretation of family and medical histories to assess the chance of disease occurrence or recurrence.
- Education about inheritance, testing, management, prevention, resources and research.
- Counseling to promote informed choices and adaptation to the risk or condition.
At the
Center for Medical genetics, all patients would be counseled by lab Director
in-charge of the Center at Chennai and or by one of the expert team members
from USA and the Medical Director.
Gene Molecular Analysis
- Microarray
- FISH (Fluorescent In-Situ Hybridization)
Prenatal
- 210H (Congenital Adrenal Hyperplasia – CAH)
- TSC1 (Tuberous Sclerosis)
- TSC2 (Tuberous Sclerosis)
- TSC 1 & 2
- HBA 1 & 2 (α – Thalassemia)
- HBB (β – Thalassemia)
- Cystic Fibrosis (CFTR)
Oncology
- BRCA 1
- BRCA 2
- BRCA 1 & 2 together
- BRAF
- EGFR: RT-PCR
- STK11 (Peutz-Jeger’s Syndrome)
- APC (Familial Adenomatous Polyposis)
- VHL Gene
- JAK2
- KRAS
- IDH1
- TP53
- PTEN
- PIK3CA
- KIT – 2 Exons/ 4 Exons (Rare)
- PDGFRA – 2 Exons
- RET Oncogene – 2 Exons/ 8 Exons
- BCR- ABL: RT – PCR
- Imatinib Resistance Mutation Analysis (IRMA)
Cardiopanel
- Warfarin Dosage
- Clopidogrel Dosage
- Cardiomyopathy Predisposition
- Statin Induced Myopathy Predisposition
- Cardiopanel (All the four tests together)
Investigative
- Human Exome Sequencing
- Whole Genome Sequencing
- Mitochondrial Genome Sequencing
- Targeted Disease Gene Panel
Training & Research @ Center for Medical
Genetics
Center
for Medical Genetics also offering various Short Term Course and Workshop in
Research Methodology and it is also approved Ph D Training Institute for
Researches.
For More details, Please
Contact / Write to us :
Dr. G
Kumaramanickavel, MD
Medical
Director
Center for Medical Genetics
3rd
Floor, Tami Nadu Foundation, 27, Taylors Road, Kilpauk,Chennai 600010, India / Ph: +91-44-42823289, +91-9789078851
/ Email: center4mgenetics@gmail.com
